Review articles


BMP Signalling at the Crossroad of Liver Fibrosis and Regeneration.

Herrera B, Addante A, Sánchez A.
Int J Mol Sci. 2017 Dec 23;19(1). pii: E39. doi: 10.3390/ijms19010039. Review.

Potential roles of bone morphogenetic protein (BMP)-9 in human liver diseases.

B. Herrera, S. Dooley, K. Breitkopf-Heinlein.
Int J Mol Sci. 2014 Mar 25;15(4):5199-220. doi: 10.3390/ijms15045199.

Moving towards personalised therapy in patients with hepatocellular carcinoma: the role of the microenvironment.

Giannelli G, Rani B, Dituri F, Cao Y, Palasciano G.
Gut. 2014 Oct;63(10):1668-76. doi: 10.1136/gutjnl-2014-307323. Review.

Role of the tissue microenvironment as a therapeutic target in hepatocellular carcinoma.

Rani B, Cao Y, Malfettone A, Tomuleasa C, Fabregat I, Giannelli G.
World J Gastroenterol. 2014 Apr 21;20(15):4128-40. doi: 10.3748/wjg.v20.i15.4128. Review.

TGF-β in hepatic stellate cell activation and liver fibrogenesis: Update.

Dewidar, B, Soukupova, J, Fabregat, I, Dooley, S.
Curr Pathobiol Rep. 2015., 3, 291-305.

Transforming growth factor β and bone morphogenetic protein actions in brain tumors.

Caja L, Bellomo C, Moustakas A.
FEBS Lett. 2015 Jun 22;589(14):1588-97. doi: 10.1016/j.febslet.2015.04.058. Review.

Role of NADPH oxidases in the redox biology of liver fibrosis.
Crosas-Molist E, Fabregat I.
Redox Biol. 2015 Dec;6:106-11. doi: 10.1016/j.redox.2015.07.005. Review.

Cross-Talk Between TGF-β and NADPH Oxidases During Liver Fibrosis and Hepatocarcinogenesis.

Crosas-Molist E, Bertran E, Fabregat I.
Curr Pharm Des. 2015;21(41):5964-76. Review.

The Rationale for Targeting TGF-β in Chronic Liver Diseases.

Giannelli G, Mikulits W, Dooley S, Fabregat I, Moustakas A, Ten Dijke P, Portincasa P, Winter P, Janssen R, Leporatti S, Herrera B, Sanchez A.Eur J Clin Invest. 2016 Jan 29. doi: 10.1111/eci.12596. [Epub ahead of print] Review.

TGF-β Signaling and Liver Disease.

Fabregat IMoreno-Càceres J, Sánchez A, Dooley S, Dewidar B, Giannelli G, Ten Dijke P
IT-LIVER Consortium. FEBS J. 2016 Jan 25. doi: 10.1111/febs.13665. [Epub ahead of print]

Transforming growth factor β as regulator of cancer stemness and metastasis.
Bellomo C, Caja L, Moustakas A.
Br J Cancer. 2016 Sep 27;115(7):761-9. doi: 10.1038/bjc.2016.255. Review.

New Insights into the Crossroads between EMT and Stemness in the Context of Cancer.

Fabregat I, Malfettone A, Soukupova J.
J Clin Med. 2016 Mar 12;5(3). Review

Evolving Insights on Metabolism, Autophagy, and Epigenetics in Liver Myofibroblasts.

Nwosu ZC, Alborzinia H, Wölfl S, Dooley S, Liu Y.
Front Physiol . 2016 Jun 1;7:191. doi: 10.3389/fphys.2016.00191. Review.

Caveolin-1 in the regulation of cell metabolism: a cancer perspective.

Nwosu ZC, Ebert MP, Dooley S, Meyer C
Molecular Cancer (2016) 15:71 DOI 10.1186/s12943-016-0558-7; Review